Imodium (or its generic form, Loperamide Hydrochloride) is a modified opioid drug. One of the effects of opium is decreased intestinal motility, meaning that it works wonders to stop diarrhea. However, unlike a full opioid, Loperamide does not cross the blood-brain barrier, so you won't experience euphoria every time you pop one to stop the diarrhea.
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